Table S1.
Parameter values used in the freely jointed chain simulations of Chr III
| Parameter | Value used in the model (range tested in MLE) |
| Mean nuclear radius (a) | 1.1 μm (0.8–1.2 μm) |
| SD of nuclear radius | 0.12 μm (0.04–0.14 μm) |
| Nucleolar volume fraction (VN) | 35% of the volume of a sphere of radius 1.1 μm (0–35%) |
| Chromosome extension parameter (γ) | 13 μm2/Mbp (3–13 μm2/Mbp) |
| FFAT association with nuclear envelope (pLacO-Teth) | 80% (50–86%) |
| SPB to centromere distance | 0.050 μm (0–0.200 μm) |
| Kuhn length | 0.200 μm (see ref. 21) |
| HML association with MAT [pL(t)] | 0 (before the DNA break), [0,1] (after the DNA break) |
The ranges of values tested during maximum likelihood estimation are shown in parentheses.