Table S1.
No difference in ventricular myocyte morphology between genotypes
Measurement | WT (n = 63, N = 6) | Scn8aN1768D/+ (n = 134, N = 5) | P value |
Cell length (µm) | 107.7 ± 2.5 | 104.8 ± 1.6 | 0.32 |
Cell width (µm) | 17.52 ± 0.40 | 17.42 ± 0.32 | 0.85 |
WT (n = 13, N = 6) | Scn8aN1768D/+ (n = 16, N = 5) | ||
Capacitance (pF) | 97.3 ± 7.7 | 83.9 ± 6.7 | 0.20 |
Images of freshly isolated ventricular myocytes were acquired within 1 h postisolation. Cell length and width were measured by an investigator blinded to genotype. Cellular capacitance was measure during AP recordings.