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. Author manuscript; available in PMC: 2016 Nov 16.
Published in final edited form as: Exp Cell Res. 2014 Jul 22;329(1):148–153. doi: 10.1016/j.yexcr.2014.07.017

Figure 2. Histone dynamics at the core of the interplay between the DDR and transcription.

Figure 2

DNA damage-induced histone dynamics, including histone exchange and post-translational modifications, govern local changes in chromatin transcriptional activity. Conversely, chromatin transcriptional state, via histone modifications, modulates DNA damage signaling and repair.