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The TP53 locus with relevant elements expanded and highlighted. Yellow boxed element, proposed mRNA stem‐loop structure 51. Red sequence, major transcription initiation site 51. Purple boxes, p53 response elements; red line, minimal internal promoter region 20. Red boxes, ATG start sites. Black box, Kozak consensus sequence 52. Lollipops, single CpG site. Base numbering from GenBank NC_000017 (7512445..7531642) as per (http://p53.iarc.fr/TP53Sequence_NC_000017-9.aspx).
