Table 1.
Baseline patient and injury characteristics as a function of resuscitation strategy
| Overall | Resuscitation Strategy |
p-value | |||
|---|---|---|---|---|---|
| Restrictive (<4cc/kg/T BSA) | Standard (4-6cc/kg/TBSA) | Excessive (>6cc/kg/TBSA) | |||
| Total patients | 330 | 109 | 128 | 93 | |
| Center | <0.001 | ||||
| 1 | 104 (31%) | 26 (25%) | 59 (57%) | 19 (18%) | |
| 2 | 81 (25%) | 21(26%) | 28 (35%) | 32 (40%) | |
| 3 | 87 (26%) | 27 (31%) | 27 (31%) | 33 (38%) | |
| 4 | 6 (2%) | 1 (17%) | 3 (50%) | 2 (33%) | |
| 5 | 52 (l6%) | 34 (65%) | 11 (21%) | 7 (13%) | |
| Mean Age (SD) | 41.3 (15.8) | 40.9 (15.5) | 40.8 (15.6) | 42.3 (16.6) | NS |
| Gender (male) | 247 (75%) | 86 (79%) | 92 (72%) | 69 (74%) | NS |
| Mean Weight, kg (SD) | 83.5 (83.5) | 89.9 (21.6) | 83.6 (21.1) | 75.7 (17.4) | <0.001* |
| Mean % TBSA, (SD) | 41.0 (18.2) | 42.4 (19.1) | 41.8 (18) | 38.1 (17.3) | NS |
| Mean %Total full-thickness (SD) | 31.0 (19.1) | 29.3 (20.1) | 32.3 (17.2) | 31.1 (20.3) | NS |
| Burn Mechanism | |||||
| Flame | 276 (84%) | 85 (78%) | 112 (88%) | 79 (85%) | NS |
| Flash | 22 (7%) | 10 (9%) | 5 (4%) | 7 (8%) | NS |
| Scald | 17 (5%) | 8 (7%) | 6 (5%) | 3 (3%) | NS |
| Other | 15 (5%) | 6 (6%) | 5 (4%) | 4 (4%) | NS |
| Inhalation injury | 129 (39%) | 28 (26%) | 61 (48%) | 40 (43%) | <0.001† |
| Mean APACHE II Score (SD) | 20.8 (9.2) | 16.0 (8.5) | 22.3 (8.8) | 24.2 (8.1) | <0.001† |
| Mean Initial base deficit (SD) | −5.14 (4.9) | −4.59 (5.0) | −5.41 (4.8) | −5.27 (4.9) | NS |
| Mean 24 Hour Fluids, L (SD) | 16.4 (10.0) | 10.3 (5.6) | 17.2 (8.5) | 22.3 (11.9) | <0.001‡ |
*
Post hoc testing revealed significant differences on these values between Standard and Excessive groups
†
Post hoc testing revealed significant differences on these values between Restrictive and Excessive groups
‡
Post hoc testing revealed significant differences on these values between all groups