Table 1.
Comparison of the Full and Study Cohort by Reproductive Health Characteristics
| Full cohort (n = 473) | Study sample (n = 214)a | |||
|---|---|---|---|---|
| Reproductive characteristic | Endometriosis (n = 190), n (%) | No endometriosis (n = 283), n (%) | Endometriosis (n = 72), n (%) | No endometriosis (n = 142), n (%) |
| Chronologic age (years) | ||||
| <30 | 75 (39.5) | 88 (31.2)b | 22 (30.6) | 34 (23.9) |
| 30–39 | 83 (43.7) | 120 (42.6) | 29 (40.3) | 65 (45.8) |
| >40 | 32 (16.8) | 74 (26.2) | 21 (29.2) | 43 (30.3) |
| Mean (SD) | 32 (6.8) | 34 (7.1)b | 34 (6.4) | 35 (6.3) |
| Gynecologic age (years) | ||||
| <10 | 68 (62.4) | 118 (57.0) | 41 (56.9) | 74 (52.1) |
| 10–15 | 31 (28.4) | 63 (30.4) | 24 (33.3) | 48 (33.8) |
| >16 | 10 (9.2) | 26 (12.6) | 7 (9.7) | 20 (14.1) |
| Mean gynecologic age (SD) | 8.9 (4.4) | 9.1 (5.3) | 9.4 (4.5) | 9.8 (5.4) |
| BMI (weight in kg/height in m2) | ||||
| Undernormal weight (<25.0) | 105 (55.6) | 98 (35.1)c | 34 (47.2) | 49 (35.0) |
| Overweight (25.0–29.9) | 39 (20.6) | 70 (25.1) | 18 (25.0) | 35 (25.0) |
| Obese (>30.0) | 45 (23.8) | 111 (39.8) | 20 (27.8) | 56 (40.0) |
| Mean (SD) | 26 (7.2) | 29 (8.4)c | 27 (7.8) | 29 (8.1) |
| Body figure rating at 15–19 years26 | ||||
| 1 | 33 (17.4) | 35 (12.4)b | 15 (20.8) | 19 (13.4) |
| 2 | 34 (17.9) | 60 (21.3) | 12 (16.7) | 30 (21.1) |
| 3 | 70 (36.8) | 74 (26.2) | 25 (34.7) | 40 (28.2) |
| 4 | 36 (18.9) | 61 (21.6) | 13 (18.1) | 29 (20.4) |
| >5 | 17 (8.9) | 52 (18.4) | 7 (9.7) | 24 (16.9) |
| Mean (SD) | 2.9 (1.2) | 3.2 (1.5)b | 2.8 (1.3) | 3.2 (1.6) |
| Age at menarche (years) | ||||
| <9 | 1 (0.5) | 0 (0.0) | 1 (1.4) | 0 (0.0) |
| 9–11 | 39 (20.5) | 50 (17.7) | 13 (18.1) | 22 (15.5) |
| 12 | 45 (23.7) | 75 (26.6) | 19 (26.4) | 39 (27.5) |
| 13–15 | 90 (47.4) | 138 (48.9) | 34 (47.2) | 71 (50.0) |
| ≥16 | 15 (7.9) | 19 (6.7) | 5 (6.9) | 10 (7.0) |
| Mean (SD) | 13 (1.8) | 13 (1.6) | 13 (1.9) | 13 (1.5) |
| Ever sexually active | ||||
| No | 27 (14.2) | 37 (13.2) | 7 (9.7) | 18 (12.7) |
| Yes | 163 (85.8) | 244 (86.8) | 65 (90.3) | 124 (87.3) |
| Ever taken emergency contraception | ||||
| No | 157 (82.6) | 237 (85.3) | 60 (83.3) | 125 (88.0) |
| Yes | 33 (17.4) | 41 (14.7) | 12 (16.7) | 17 (12.0) |
| Ever pregnant | ||||
| No | 81 (42.6) | 74 (26.3)c | — | — |
| Yes | 109 (57.4) | 207 (73.7) | 72 (100) | 142 (100) |
| Ever tried for planned pregnancy | ||||
| No | 37 (33.9) | 65 (31.4) | — | — |
| Yes | 72 (66.1) | 142 (68.6) | 72 (100) | 142 (100) |
| Ever tried >6 months for pregnancy | ||||
| No | 96 (50.5) | 209 (74.9)c | 37 (51.4) | 98 (70.0)b |
| Yes | 94 (49.5) | 70 (25.1) | 35 (48.6) | 42 (30.0) |
| Mean longest attempt (SD) | 34 (41) | 28 (29) | 27 (41) | 27 (30) |
| Ever have live birth | ||||
| No | 105 (55.3) | 102 (36.0)c | 9 (12.5) | 9 (6.3) |
| Yes | 85 (44.7) | 181 (64.0) | 63 (87.5) | 133 (93.7) |
| Ever use infertility treatment | ||||
| No | 126 (66.3) | 235 (83.0)c | 47 (65.3) | 118 (83.1)b |
| Yes | 64 (33.7) | 48 (17.0) | 25 (34.7) | 24 (16.9) |
| Active smoking (serum cotinine ng/mL)31 | ||||
| No (<10) | 169 (88.9) | 233 (82.3)b | 67 (93.1) | 124 (87.3) |
| Yes (≥10.0) | 21 (11.1) | 50 (17.7) | 5 (6.9) | 18 (12.7) |
| Pelvic pain >6 months | ||||
| No | 106 (55.8) | 184 (65.2)b | 41 (56.9) | 98 (69.0) |
| Yes | 84 (44.2) | 98 (34.8) | 31 (43.1) | 44 (31.0) |
| Dyspareunia | ||||
| No | 54 (28.4) | 144 (50.9)c | 25 (34.7) | 71 (50.0)b |
| Yes | 136 (71.6) | 139 (49.1) | 47 (65.3) | 71 (50.0) |
| Ever avoid sex due to pelvic pain | ||||
| No | 89 (46.8) | 145 (52.0) | 34 (47.2) | 66 (46.5) |
| Yes | 101 (53.2) | 134 (48.0) | 38 (52.8) | 76 (53.5) |
| Preoperative diagnosis | ||||
| Pelvic pain | 120 (63.2) | 86 (30.5)c | 41 (56.9) | 41 (29.1)b |
| Pelvic mass | 26 (13.7) | 48 (17.0) | 6 (8.3) | 17 (12.0) |
| Irregular menses | 20 (10.5) | 40 (14.2) | 11 (15.3) | 29 (20.6) |
| Fibroids | 9 (4.7) | 40 (14.2) | 5 (7.0) | 12 (8.5) |
| Infertility | 7 (3.7) | 28 (9.9) | 2 (2.8) | 13 (9.2) |
| Tubal ligation | 8 (4.2) | 40 (14.2) | 7 (9.7) | 29 (20.6) |
| Endometriosis severity (rASR1V)34 | ||||
| Stage 1, minimal | 95 (50.0) | — | 41 (57.0) | — |
| Stage 2, mild | 39 (21.0) | — | 14 (19.0) | — |
| Stage 3, moderate | 35 (18.0) | — | 11 (15.0) | — |
| Stage 4, severe | 21 (11.0) | — | 4 (8.0) | — |
Chi-square or Wilcoxon continuous tests were used to compare women with and without endometriosis.
a
Restricted to women reporting ever having planned a pregnancy.
b
p < 0.05.
c
p < 0.001.
SD, standard deviation; —, not applicable for estimation, in that all women were defined as having tried for pregnancy with a known time to pregnancy in the study sample.