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HBV persistence in mice after hydrodynamic injection of HBV plasmids is related to the genetic background of the recipients. Male (A) AAVS1, (B) BALB/c, (C) C57BL/6, and (D) C3H/HeJ mice (group size: n=5) were injected hydrodynamically with 10 μg of HBV plasmid. HBsAg and HBeAg titer in the mouse serum was detected using the chemiluminescent enzyme immunoassay (CLEIA) system kit (Wantai, China).
