Fig. 7.
Semi-logarithmic graph of the concentration-time profiles (Mean ± SD) of norketamine in Sprague-Dawley rats (n=6/group; standard housing cage (SDC), multilevel housing cage (MLC)) following the intraperitoneal administration of ketamine (80 mg/kg) and xylazine (10 mg/kg). A peak at time point 1 hr can be observed in the rats housed in SDC, compared to rats housed in MLC (*P<0.05).