Table 2. Left ventricular wall motility in WHHLMI rabbits with coronary spasm.
| Left ventricular diameter (mm) | Fractional shortening | |||
|---|---|---|---|---|
| Diastole | Systole | |||
| Normal JW rabbits (n=7) | 13.2 ± 1.0 | 7.8 ± 0.8 | 41.5 ± 3.1 | |
| WHHLMI rabbits (n=13) | ||||
| Baseline | 14.5 ± 1.0 | 9.8 ± 0.6 | 32.5 ± 1.2* | |
| Norepinephrine infusion | 15.1 ± 0.5 | 10.6 ± 0.4 | 29.7 ± 1.3 | |
| Norepinephrine + Ergonovine | 15.1 ± 0.7 | 11.6 ± 0.5# | 23.0 ± 0.6## | |
Data are represented as the mean ± SEM. Statistical analyses were performed with the Student’s t-test for differences between normal and WHHLMI rabbits, and with the Bonferroni test for WHHLMI rabbits in the coronary vasospasm provocation test. *, P=0.004 (JW vs. WHHLMI); #, P=0.009 (baseline vs. the combination treatment); ##, P<0.001 (baseline vs. the combination treatment).