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. Author manuscript; available in PMC: 2017 Aug 1.
Published in final edited form as: Semin Oncol. 2016 Jun 15;43(4):476–483. doi: 10.1053/j.seminoncol.2016.06.005

Figure 3.

Figure 3

Response to the drug lapatinib (IC50 values capped at 8.0) vs. phospho-EGFR expression in lung cancer cell lines. IC50 is inversely correlated with phospho-EGFR expression (Pearson correlation = −0.465, P-value = 0.00077), indicating that cell lines with higher expression of phospho-EGFR are more sensitive to the drug. The line of best fit is shown in red. Correlation with these previously-known findings further validate the data produced by the RPPA platform and the methods described.