Table 5.
Predicted activated upstream regulators of stromal/epithelial comparison using IPA
| Upstream Regulator | Log Ratio | Predicted Activation State | Activation z-Score | P Value of Overlap |
|---|---|---|---|---|
| TP53 | −0.44 | activated | 5.19 | 1.52E-30 |
| CEBPA | 0.20 | activated | 4.09 | 6.27E-05 |
| HTT | 0.02 | activated | 3.84 | 9.28E-11 |
| CTNNB1 | 0.18 | activated | 2.83 | 4.18E-20 |
| MITF | 0.59 | activated | 2.77 | 4.90E-05 |
| POU5F1 | −0.20 | activated | 2.77 | 2.84E-02 |
| EGR1 | 0.41 | activated | 2.75 | 7.40E-04 |
| JUNB | 0.21 | activated | 2.64 | 8.64E-05 |
| FOXF1 | 4.00 | activated | 2.63 | 3.79E-08 |
| PAX6 | −0.38 | activated | 2.57 | 1.07E-02 |
IPA, Ingenuity Pathway Analysis.