Table 1.
Anthropometric and biochemical data of subjects
Control subjects | Type 2 diabetic patients | |
(n = 43) | (n = 45) | |
Male/female ratio | 23/20 | 21/24 |
Age | 30–54 yr | 30–55 |
BMI (kg/m2) | 25.19 ± 1.90 | 26.38 ± 0.92 |
Duration of disease (years) | - | 9.9 ± 2.3 |
Insulin treatment (% patients receiving insulin treatment) |
No | Yes (100%) |
Fasting glucose (mM) | 5.05 ± 0.17 | 9.55 ± 1.11** |
HbA1C (%) | 4.25 ± 0.25 | 9.57 ± 1.56** |
Insulinemia (µUI/ml) | 5.46 ± 0.77 | 10.93 ± 0.64** |
Urea (mM) | 5.33 ± 0.33 | 5.49 ± 0.17 |
Creatinemia (µM) | 95.38 ± 6.31 | 98.30 ± 6.10 |
Total cholesterol (mM) | 5.64 ± 0.41 | 4.35 ± 0.36* |
HDL-cholesterol (mM) | 1.63 ± 0.03 | 1.55 ± 0.05 |
Triglycerides (mM) | 1.23 ± 0.13 | 0.83 ± 0.11* |
BMI: Body Mass Index; HDL: High Density Lipoproteins; HbA1c: glycosylated hemoglobin. Values are means ± SEM. n = 43 healthy control subjects; n = 45 type 2 diabetic patients. *p<0.05 and **p<0.01 indicate significant difference between type 2 diabetic patients and healthy control subjects. Ranges of normal values: Fasting glucose: 3.88–6.10 mM (0.7–1.10 g/L); Total-cholesterol: 3.23–6.46 mM (1.25–2.50 g/L) ; HDL-cholesterol: 1.16–1.94 mM (0.45–0.75 g/L); Triglycerides: 0.57–1.71 mM (0.50–1.50 g/L); Urea: 2.50–7.49 mM (0.15–0.45 g/L) ; Creatinine: 53.04–123.76 µM (6–14 mg/L) ; HbA1c: 4–6 % ; Insulin: 1.21–14.5 µUI/ml.