Fig 2 Patient flow showing loss to follow-up, withdrawal, and missing data by study arm and outcome assessment period. Counts below randomisation are accumulative, with numbers in each box adding up to total number of patients allocated to given arm. Withdrawn=patients who actively refused to participate in further treatment or follow-up; lost to follow-up=patients who could not be contacted for current month assessment; missing FAOS=patients for whom FAOS at specified time point was not obtained