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. 2016 Nov 17;10:263. doi: 10.3389/fncel.2016.00263

FIGURE 1.

FIGURE 1

Diagram of autism-risk genes implicated in regulating the structural stability of neurons. Each circle represents a cellular pathway to regulate the structural stability of neurons, including neurite outgrowth (red), dendritic spine or synapse formation (blue), and synaptic plasticity (gold). Experimental evidence shows that many autism-risk genes regulate at least one cellular pathway to maintain the integrity of neuronal structures. Genes that regulate only one pathway are labeled in light gray. Genes that regulate two pathways are labeled in dark gray. Genes that regulate three pathways are labeled in black. The summaries of autism-risk genes that affect each cellular pathway can be found in Tables 13.