Table 2.
Composition of the topical gel formulations.
| Amount of each ingredient (%); formulations are coded from 1 to 18 | ||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Ingredients | G1 | G2 | G3 | G4 | G5 | G6 | G7 | G8 | G9 | G10 | G11 | G12 | G13 | G14 | G15 | G16 | G17 | G18 |
| Zinc sulfate | 3 | |||||||||||||||||
| Copper sulfate | 3 | |||||||||||||||||
| ι-Carrageenan | 2 | 1 | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — |
| 5% HPMC gel | — | — | qs 100 | qs 100 | 50 | 25 | — | — | — | — | — | — | — | — | — | — | — | — |
| Xanthan gum | — | — | — | — | — | — | 2 | — | — | — | — | — | — | — | — | — | — | — |
| Guar gum | — | — | — | — | — | — | — | 2 | — | — | — | — | — | — | — | — | — | — |
| Poloxamer 407 | — | — | — | — | — | — | — | — | 32 | 24 | 16 | — | — | — | — | — | — | — |
| Lecithin | — | — | — | — | — | — | — | — | 10 | 10 | 10 | — | — | — | — | — | — | — |
| Isopropyl myristate | — | — | — | — | — | — | — | — | 10 | 10 | 10 | — | — | — | — | — | — | — |
| Kollidon 90F | — | — | — | — | — | — | — | — | — | — | — | 30 | 20 | 10 | — | — | — | — |
| FlexiThix | — | — | — | — | — | — | — | — | — | — | — | — | — | — | 6 | 4 | 2 | — |
| Carbomer 940 | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | 1 |
| Triethanolamine | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | 1.35 |
| BHT | — | — | — | — | — | — | — | — | 0.05 | 0.05 | 0.05 | — | — | — | — | — | — | — |
| DI water | qs ad to 100 | — | 25 | qs ad to 100 | ||||||||||||||
HPMC: hypromellose; BHT: butylated hydroxytoluene.