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. 2016 Nov 17;7:200. doi: 10.3389/fgene.2016.00200

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Copyright © 2016 North, Gaytán, Romero, De La Rosa, Loguinov, Smith, Zhang and Vulpe.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Determining the FA IC₂₀ for functional screens. (A) Representative growth curves in YPD media for the wild-type BY4743 strain exposed to FA. For clarity, the 0.2 mM FA curve is not shown. (B) The area under the curve (AUC) was determined for each FA dose from three independent growth curve experiments, expressed as the mean and SE, and plotted as a percentage of the untreated control. The FA IC₂₀ was calculated to be about 0.6 mM (600 μM).