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. 2016 Nov 8;4(21):e13016. doi: 10.14814/phy2.13016

Figure 3.

Figure 3

Macroscopic and histopathological findings in mice fed with steatohepatitis‐inducing high‐fat diet (STHD‐01) for 30 weeks after diethylnitrosamine (DEN) pretreatment. Macroscopic findings in the liver of mice fed with standard diet (SD) or STHD‐01 for 30 weeks immediately after switching from drinking water containing 0.04% DEN for 10 days to normal drinking water (A). Histopathological findings in the liver. Hepatocellular carcinoma with structural and cellular atypia in a mouse fed with STHD‐01 for 30 weeks after DEN pretreatment (B). Frequency of tumor formation (C).