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. 2016 Nov 15;4(21):e13020. doi: 10.14814/phy2.13020

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© 2016 The Authors. Physiological Reports published by Wiley Periodicals, Inc. on behalf of The Physiological Society and the American Physiological Society.

This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

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Enhanced resistance of idiopathic pulmonary fibrosis (IPF) fibroblasts to the A. alternata extract‐induced cell death. Randomly selected control and IPF fibroblasts (n = 8, each) were stimulated with 100 μg/mL of A. alternata extract (lot no. 169626) as a function of time (A) or with various doses of A. alternata extract (lot no. 169626) for 8 h (B). Values given in A are the average ± SEM as the percentage against their respective nontreatment group (0 h), set at 100%. On the scatterplot in B, each circle and triangle point represents the percentage of viability of each control and IPF cell in response to A. alternata extract against their respective nontreatment groups (0 μg/mL), set at 100%. (*) indicates statistical significance between control and IPF fibroblasts at P < 0.05.