Table 3. Odds ratio (95% confidence interval) of nonalcoholic fatty liver disease according to quartiles of plasma selenium concentrations.
Quartile 1 | Quartile 2 | Quartile 3 | Quartile 4 | P for trend | |
---|---|---|---|---|---|
<181.6 μg/L | 181.6–213 μg/L | 213.1–247.4 μg/L | >247.4 μg/L | ||
No. cases/participants | 613/2212 | 809/2213 | 1145/2212 | 1165/2213 | |
Model 1a | 1 | 1.29 (0.99–1.77) | 1.79 (1.26–2.37) | 1.60 (1.17–2.18) | <0.001 |
Model 2b | 1 | 1.29 (0.98–1.78) | 1.75 (1.22–2.34) | 1.58 (1.15–2.18) | <0.001 |
Model 3c | 1 | 1.24 (0.96–1.77) | 1.70 (1.16–2.32) | 1.52 (1.11–2.14) | <0.001 |
Model 4d | 1 | 1.27 (0.95–1.77) | 1.72 (1.19–2.33) | 1.54 (1.13–2.18) | <0.001 |
aModel 1: adjusted for age, gender.
bModel 2: additionally adjusted for BMI, current smoking status, drinking status, physical activity.
cModel 3: additionally adjusted for waist circumference, systolic blood pressure, diastolic blood pressure, fasting plasma glucose, post-loading plasma glucose, HOMA-IR, lipid profiles and estimated glomerular filtration rate.
dModel 4: additionally adjusted for liver enzyme profiles and C-reactive protein.