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. 2016 Nov 17;6:37323. doi: 10.1038/srep37323

Table 1. Effects of compounds 3a and 3f on the biochemical parameters of normal and diabetic rats.

Biochemical Parameter Normal Control Diabetic Control Pioglitazone 15 mg/kg Compound 3a 15 mg/kg Compound 3f 15 mg/kg
FFA (mmol/L) 0.16 ± 0.03 0.21 ± 0.01a 0.15 ± 0.01b 0.17 ± 0.03b 0.16 ± 0.02b
HDL-c (mmol/L) 0.83 ± 0.01 0.61 ± 0.16a 0.72 ± 0.15b 0.64 ± 0.09 0.66 ± 0.12b
LDL-c (mmol/L) 0.24 ± 0.03 2.92 ± 1.13a 1.60 ± 0.14b 1.35 ± 0.25b 1.17 ± 0.43b
TC (mmol/L) 1.53 ± 0.18 8.91 ± 3.44a 5.20 ± 1.25b 4.71 ± 0.51b 3.81 ± 1.23b
TG (mmol/L) 0.71 ± 0.05 1.18 ± 0.21a 0.66 ± 0.23b 0.68 ± 0.21b 0.49 ± 0.23b

All values are expressed as the means ± SD. The level of significance was determined by one-way ANOVA, followed by the Bonferroni post hoc test. aP < 0.01 versus the normal control. bP < 0.05 versus the diabetic control.