Table 2. Levels of amino acids and their ratios in the frontal cortex, hippocampus and striatum of the adult offspring after MIA.

	Glutamate	Glutamine	Glycine	L-Serine	D-Serine	GABA
Frontal cortex
Control	9.394 ± 0.201	5.114 ± 0.162	0.728 ± 0.022	0.742 ± 0.022	0.370 ± 0.011	2.492± 0.050
Poly(I:C)	8.953 ± 0.140	4.777 ± 0.111	0.722 ± 0.015	0.697 ± 0.020	0.333 ± 0.009*	2.544 ± 0.062
Hippocampus
Control	9.816 ± 0.147	5.165 ± 0.113	0.909 ± 0.016	0.860 ± 0.018	0.354 ± 0.009	2.562 ± 0.054
Poly(I:C)	9.361 ± 0.134*	4.911 ± 0.094	0.967 ± 0.026	0.735 ± 0.014***	0.284 ± 0.007***	2.675 ± 0.071
Striatum
Control	8.128 ± 0.189	5.537 ± 0.154	0.921 ± 0.029	0.815± 0.022	0.320 ± 0.009	2.973 ± 0.093
Poly(I:C)	8.562 ± 0.172	5.636 ± 0.127	1.015 ± 0.025*	0.745 ± 0.012*	0.288 ± 0.007**	3.182 ± 0.101
	Glutamine/Glutamate	L-Serine/Glycine	D-Seri/L-Serinene	GABA/Glutamate
Frontal cortex
Control	1.848 ± 0.043	1.027 ± 0.037	0.499 ± 0.005	0.267 ± 0.008
Poly(I:C)	1.883 ± 0.040	0.967 ± 0.021	0.478 ± 0.007*	0.285 ± 0.007
Hippocampus
Control	1.909 ± 0.043	0.949 ± 0.020	0.412 ± 0.008	0.262 ± 0.006
Poly(I:C)	1.911 ± 0.031	0.765 ± 0.021***	0.387 ± 0.007*	0.286 ± 0.006*
Striatum
Control	1.475 ± 0.033	0.892 ± 0.027	0.394 ± 0.009	0.369 ± 0.016
Poly(I:C)	1.523 ± 0.026	0.738 ± 0.016***	0.386 ± 0.004	0.373 ± 0.013

Data (nmol/mg tissue) are expressed as the mean ± SEM (Control: n = 13, Poly(I:C): n = 13). *P < 0.05, **P < 0.01, ***P < 0.001 compared to control group (Student’s t test).