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. 2016 Nov 17;6:37270. doi: 10.1038/srep37270

Figure 2. CD133+ cells limit injury markers in AKI SCID model.

Figure 2

(A) Changes in renal function were measured by BUN. Mice treated with CD133+ cells showed significantly reduced levels as compared to controls. Data are the mean ± SD of 6 mice/experiment (PBS and CD133+ cells) or 3 mice/experiment (Normal or Fibroblasts). (B) qRT-PCR analysis of whole mice kidney lysates of normal and AKI mice showing decrease of injury, inflammatory and pro-fibrotic markers in mice that received CD133+ cells as compared to PBS or fibroblasts. Data are mean ± SD of three independent experiments and are normalized to GAPDH mRNA and to 1 for normal and expressed as relative quantification (RQ). ANOVA with Newman Keuls’ multicomparison test was performed: §p < 0.01 versus Normal; *p < 0.01 versus PBS, #p < 0.01 versus fibroblasts.