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. 2016 Nov 17;6:37268. doi: 10.1038/srep37268

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Copyright © 2016, The Author(s)

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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(a) The expression of COL2A1, aggrecan, MMP1, MMP13, and ADAMTS5 was analyzed by qPCR in chondrocytes with CTS and control. The results are expressed as mean ± SEM of at least three independent experiments (*P < 0.05, **p < 0.01). (b) Toluidine blue staining and Alcian blue staining for chondrocytes stimulated with CTS and control.