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. 2016 Nov 17;6:37225. doi: 10.1038/srep37225

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Copyright © 2016, The Author(s)

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CEM CD4⁺ T cells expressing (NT) or depleted (SH) of BST2 were infected with CCR5-tropic NL4.3.ADA.IRES.GFP WT, N-U- or N-U-D368A viruses as indicated in Fig. 2 legend and examined for ADCC susceptibility mediated by (a) CD4-non-induced PGT126 or (b) CD4i 17b Abs as described in Fig. 1 legend. Panels a and b summarize results from at least 4 donors. In both Panels, paired, two-tailed Student’s t-tests, were used to compare the effect of BST2 depletion on ADCC activity with each virus.