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. 2016 Nov 17;6:37094. doi: 10.1038/srep37094

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Copyright © 2016, The Author(s)

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(A) NHP 1 targeting putamen at 275 kPa. (B) NHP 2 targeting caudate nucleus and putamen at 400 kPa. (C) NHP 3 targeting putamen at 450 kPa. (D) NHP 4 targeting caudate nucleus and putamen at 600 kPa. No edema or hemorrhage was detected in any of the cases. 1^st row: contrast enhancement of the BBB opening overlaying onto the post-Gd T_1w imaging; 2^nd row: T_2w imaging for edema; 3^rd row: susceptibility-weighted imaging (SWI) for hemorrhage.