Figure 2. Pancreas-specific uptake of ¹⁸F-L-FEHTP in wt and Akita mice.

a) Ex vivo tracer uptake was calculated for the pancreas of wt (n=6) and Akita (n=6) mice as % ID/g tissue at 1.5 h after injection. b) PET imaging of the pancreas after injection of ¹⁸F-L-FEHTP. One hour after injection, static images were acquired for 30 min. Representative images of wt (n=6) and Akita (n=5) mice show highly specific uptake in the pancreas with little detectable background uptake. Arrowheads indicate position of the pancreas. Arrows indicate position of spleen.