Table 1. Ex vivo biodistribution of 18F-L-FEHTP in wt and Akita mice.
Organ | Akita | Wild-type | |
---|---|---|---|
Heart | 6.94±4.7 | 14.58±9.4 | |
Pancreas | 43.81±24.7 | 35.47±6.7 | |
Blood | 6.32±4.1 | 2.31±0.5 | |
Lung | 3.52±1.5 | 0.43±0.1 | |
Liver | 4.32±1.9 | 17.89±4.2 | ** |
Spleen | 16.57±13.4 | 3.25±1.1 | |
Stomach | 5.77±3.4 | 2.42±0.6 | |
Intestine | 3.76±1.4 | 3.69±1.0 | |
Kidney | 11.36±5.4 | 7.64±1.6 | |
Thymus | 12.06±9.9 | 2.74±0.7 | |
Muscle | 19.53±16.5 | 5.49±2.3 | |
Tail | 5.79±2.3 | 2.45±0.6 | |
Brain | 3.50±1.6 | 2.76±0.7 |
Values are expressed as %ID/g tissue, and are means ± SEM (n=6). ** p< 0.01 compared to wt.