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Figure 2. Summary of kinase alterations documented in histiocytic neoplasms.
Somatic mutations described in (A) BRAF and ARAF, (B) MAP2K1 and MAP3K1, (C) H/N/KRAS, and (D) PIK3CA and PIK3CD, as well as fusions in (E) BRAF, (F) ALK, (G) NTRK1 and (H) ETV3-NCOA2.