Table 3. Prevalence of allele frequencies in the Jing and Han populations [n(%)].
| Mutation | Allele | Jing (n = 1272) | Han (n = 1280) | X2 | P-value |
|---|---|---|---|---|---|
| AGBL4 rs320017 | A/G | 1974(77.59)/570(22.41) | 2060(80.47)/500(19.53) | 6.363 | 0.012 |
| AGBL4 rs320018 | A/G | 1967(77.32)/577(22.68) | 2051(80.12)/509(19.88) | 5.964 | 0.015 |
| AGBL4 rs320019 | G/A | 1976(77.67)/568(22.33) | 2055(80.27)/505(19.73) | 5.197 | 0.023 |
| LRP8 rs6694764 | G/A | 1442(56.68)/1102(43.32) | 1541(60.20)/1019(39.80) | 6.484 | 0.011 |
| LRP8 rs1288519 | A/C | 1468(57.70)/1076(42.30) | 1565(61.13)/995(38.87) | 6.220 | 0.013 |
| LRP8 rs872315 | G/A | 2448(96.23)/96(3.77) | 2502(97.73)/58(2.27) | 9.480 | 0.002 |
| LRP8 rs1288520 | C/T | 1452(57.08)/1092(42.92) | 1578(61.64)/982(38.36) | 11.024 | 0.001 |
| LRP8 rs1288521 | C/T | 1567(61.60)/977(38.40) | 1660(64.84)/900(35.16) | 5.789 | 0.016 |
| PCSK9 rs533375 | C/T | 2112(83.02)/432(16.98) | 2211(86.37)/349(13.63) | 11.038 | 0.001 |
| PCSK9 rs584626 | A/G | 2380(93.55)/164(6.45) | 2438(95.23)/122(4.77) | 6.816 | 0.009 |
| PCSK9 rs585131 | A/G | 2386(93.79)/158(6.21) | 2449(95.66)/111(4.34) | 8.983 | 0.003 |
| PCSK9 rs540796 | G/A | 2356(92.61)/188(7.39) | 2437(95.20)/123(4.80) | 14.904 | 1.131E-04 |
AGBL4, the ATP/GTP binding protein-like 4 gene; LRP8, the LDL receptor related protein 8 gene; PCSK9, the Proprotein convertase subtilisin/kexin type 9 gene.