Table 2.
Patient characteristics in group 2 (mixed medical-surgical)
| Clinical variables | No acute kidney injury | Acute kidney injury | Total | AKI versus no AKI p value |
|---|---|---|---|---|
| Total | 573 | 1294 | 1867 | |
| Baseline demographics | ||||
| Age, years | 56.8 ± 16.8 | 59.8 ± 18 | 58.9 ± 18 | <0.01 |
| Male sex, n (%) | 246 (43) | 543 (42) | 794 (43) | 0.78 |
| Body mass index, kg/m2 | 27.5 ± 7.7 | 28.2 ± 7.5 | 27.9 ± 7.6 | 0.09 |
| Race, n (%) | ||||
| White | 573 (100) | 1294 (100) | 1867 (100) | 1 |
| Comorbidities, n (%) | ||||
| Diabetes mellitus | 95 (17) | 331 (26) | 426 (23) | <0.01 |
| SOFA score | 7.0 ± 2.3 | 8.8 ± 2.9 | 8.3 ± 2.8 | <0.01 |
| SOFA without renal component | 6.9 ± 2.2 | 7.7 ± 2.5 | 7.5 ± 2.5 | <0.01 |
| APACHE III score | 64 ± 24.6 | 78 ± 26.8 | 74 ± 26.8 | <0.01 |
| ICU events, n (%) | ||||
| Mechanical ventilation | 416 (78) | 909 (70) | 1325 (77) | <0.01 |
| Sepsis | 325 (56) | 877 (68) | 1202 (64) | <0.01 |
| Vasopressors | 134 (35) | 571 (44) | 705 (48) | <0.01 |
| Diagnosis of ARDS | 306 (53) | 700 (37) | 1006 (54) | <0.01 |
| Clinical risk for ARDS, n (%) | ||||
| Pneumonia | 298 (52) | 702 (54) | 1000 (54) | 0.37 |
| Sepsis | 366 (64) | 1006 (78) | 1372 (73) | <0.01 |
| Aspiration | 74 (13) | 158 (12) | 232 (12) | 0.75 |
| Trauma | 57 (10) | 86 (7) | 143 (8) | 0.01 |
| Other | 23 (4) | 31 (2) | 54 (3) | 0.06 |
| Admission status, n (%) | ||||
| Direct | 518 (90) | 1192 (92) | 1710 (92) | 0.21 |
| Transfer | 55 (10) | 102 (8) | 157 (8) | |
| KDIGO stage of acute kidney injury, n (%) | ||||
| Stage 0 | 573 (100) | 0 | 573 (31) | |
| Stage 1 | 0 | 944 (73) | 944 (51) | |
| Stage 2 | 0 | 165 (13) | 165 (9) | |
| Stage 3 | 0 | 185 (14) | 185 (10) | |
Abbreviations: AKI Acute kidney injury, APACHE III Acute Physiology and Chronic Health Evaluation III, ARDS Acute respiratory distress syndrome, ICU Intensive care unit, KDIGO Kidney Disease: Improving Global Outcomes, SOFA Sepsis-related Organ Failure Assessment
Data shown as mean ± standard deviation, n (%) as appropriate