Table 5.
Exploratory analyses - Comparison of sugammadex and neostigmine on OR efficiency and clinical outcomes in an OR over 1 month when deep block is maintained to the end of all procedures [0% of patients verified to have full neuromuscular recovery (TOF ratio ≥ 0.9) prior to extubation]
| Outcome Measure | Neostigmine | Sugammadex (4 mg/kg) | |||
|---|---|---|---|---|---|
| Minutes of OR time saved per procedure | |||||
| 15 | 30 | 45 | 60 | ||
| OR efficiency outcomes | |||||
| Number of OR minutes saved per day | – | 39 | 79 | 118 | 158 |
| % of days all procedures are completed within the regular OR day | 46.7% | 61.9% | 77.1% | 86.9% | 91.4% |
| Number of procedures performed | 54.5 | 54.7 | 55.1 | 55.1 | 55.2 |
| Procedures cancelled due to lack of OR time | 1.2 | 0.7 | 0.4 | 0.4 | 0.3 |
| Procedures cancelled for other reasons | 7.3 | 7.6 | 7.6 | 7.6 | 7.6 |
| Paid hours of staff over-time | 84.1 | 54.9 | 32.0 | 18.3 | 11.5 |
| Clinical outcomes | |||||
| Cases of residual blockade avoided | – | 30 | 30 | 30 | 30 |
| Hypoxemia cases avoideda | – | 7 | 7 | 7 | 7 |
| Upper airway obstruction cases avoideda | – | 13 | 13 | 13 | 13 |
| Absolute reduction in risk of residual blockade, per patient | – | 56% | 56% | 56% | 56% |
OR Operating room
aIncludes both cases which are and are not clinically diagnosed and managed