Table 2.

Characteristics of negative and positive SIPS scores and social competences in 22q11.2DS and control peers

	22q11.2DS		Control		Main effect of group
Test	Median or mean (SD)	Min-max	Median or Mean (SD)	Min-max	z a	W or F(df,df)	p
Psychopathology
Positive symptomsb	3	0–12	0	0–9		625	7.5 × 10−4
Negative symptomsb	6	1–17	0.38	0–2		831	5.8 × 10−11
Disorganized symptomsb	1	0–9	0	0–2		723.5	1.2 × 10−07
General symptomsb	0	0–7	0	0–4		469.5	0.32
Social functioning
ABASsocial c	99.89 (18.6)	256–606	126.1 (9.26)	110–138	−2.77	61.02 (1,50)	2.9 × 10−10
Social skills
SRStotal b	64	15–122	15.17	3–44	5.00	678	6.2 × 10−9
Social cognition
TASITtotal b	38	16–56	52.83	37–58	−3.83	44.5	8.0 × 10−9
ERTtotal c	40.83 (12.09)	16.67–64.44	64.52 (7.75)	47.67–77.78	−2.96	88.07 (1,53)	7.39 × 10−13

Measures of psychopathology were obtained from the structured interview for prodromal syndromes (SIPS), The raw score obtained from the social domain of the Adaptive Behavior Assessment System (ABAS-II) was used as a measure of social function, social skills were the total score obtained from the Social Responsiveness Scale (SRS), social cognitive abilities were evaluated using total correct answers from The Awareness of Social Inference Test (TASIT) and the CANTAB Emotional Recognition Task (ERT)

^aMean z-scores for 22q11.2 group as calculated from mean control = 0 and SD = 1

^bGroup median reported; group differences determined from Wilcoxon rank-sum test

^cGroup mean reported, main effect of group accessed from two-way ANCOVA [between-group factor (22q11.2DS, controls); between subject’s factor: sex; covariate: age]