Skip to main content
. Author manuscript; available in PMC: 2016 Nov 17.
Published in final edited form as: Bioorg Med Chem. 2016 Sep 26;24(22):5969–5987. doi: 10.1016/j.bmc.2016.09.059

Figure 3.

Figure 3

HIV-1 invasion assay in human astrocytes. HIV-1SF162 infectivity in human glia was determined based on the relative amount of Tat protein expressed by the virus using a luciferase based assay. HA: human astrocytes, uninfected cells; R5: R5-tropic HIV-1; M: morphine; MVC: maraviroc; NTX: naltrexone; BIVALENT: compound 1b. Values are absorbance ± SEM of 3 independent experiments at 18 h post-infection (*p < 0.005 vs. un-infected cells; $p < 0.05 vs. R5 HIV-1; #p <0.05 vs. M; p < 0.05 vs. MVC; §p < 0.05 vs. M + MVC;^p <0.05 vs. MVC + NTX; ^^p <0.05 vs. M + MVC + NTX; Ωp <0.05 vs. bivalent).