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. Author manuscript; available in PMC: 2016 Nov 17.
Published in final edited form as: ACS Chem Neurosci. 2015 Apr 15;6(5):751–760. doi: 10.1021/acschemneuro.5b00013

Figure 6. Filament length distributions.

Figure 6

Tau disassembly reactions were performed and viewed by electron microscopy. The filaments remaining following incubation with or without compound were measured, and placed into bins according to their length (30–50 nm, 50–100 nm, 100–150 nm, 150–200 nm and > 200 nm). The lengths within a bin were summed to determine the total amount of filament length in each bin. A) Represents the length distributions for filaments in the control reaction without compound. The length distributions are also shown for filaments remaining following incubation in the presence of B) aza-7, C) aza-8, D) aza-9, E) aza-10, F) aza-11, G) aza-12, H) aza-13, I) aza-14, J) aza-15, K) aza-16, and L) aza-17. Each point is the average distribution for images of 5 different fields ± SD.*P ≤ 0.05; ** P ≤ 0.01; *** P ≤ 0.001.