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. 2016 Nov 15;13(11):e1002169. doi: 10.1371/journal.pmed.1002169

Table 2. Descriptive characteristics of patients with and without lipid-lowering, anticoagulant, and antihypertensive drugs clinically indicated at the time of their stroke or transient ischaemic attack.

Characteristic Subcategory Lipid-Lowering Drugs Clinically Indicated Anticoagulant Drugs Clinically Indicated Antihypertensive Drugs Clinically Indicated
Yes No Yes No Yes No
Diagnosis Stroke only 8,464 (52.8) 7,781 (59.8) 1,881 (58.9) 14,364 (55.6) 3,843 (54.8) 12,402 (56.3)
TIA only 5,212 (32.5) 5,234 (40.2) 958 (30.0) 9,488 (36.7) 2,253 (32.2) 8,193 (37.2)
Stroke with previous TIA 2,352 (14.7) 0 (0.0) 355 (11.1) 1,997 (7.7) 912 (13.0) 1,440 (6.5)
Total 16,028 (100) 13,015 (100) 3,194 (100.0) 25,849 (100.0) 7,008 (100.0) 22,035 (100.0)
Age (years) <45 115 (0.7) 997 (7.7) 6 (0.2) 1,106 (4.3) 69 (1.0) 1,043 (4.7)
45–49 221 (1.4) 723 (5.6) 9 (0.3) 935 (3.6) 109 (1.5) 835 (3.8)
50–54 494 (3.0) 919 (7.0) 15 (0.5) 1,398 (5.4) 190 (2.7) 1,223 (5.6)
55–59 811 (5.1) 954 (7.3) 39 (1.2) 1,726 (6.7) 311 (4.4) 1,454 (6.6)
60–64 1,489 (9.3) 1,097 (8.4) 70 (2.2) 2,516 (9.7) 556 (7.9) 2,030 (9.2)
65–69 2,049 (12.8) 1,193 (9.2) 170 (5.3) 3,072 (11.9) 832 (11.9) 2,410 (10.9)
70–74 2,638 (16.5) 1,083 (8.3) 291 (9.1) 3,430 (13.3) 1,091 (15.6) 2,630 (11.9)
75–79 2,329 (14.5) 2,069 (15.9) 604 (18.9) 3,794 (14.7) 1,133 (16.2) 3,265 (14.8)
80–84 2,514 (15.7) 1,791 (13.8) 760 (23.8) 3,545 (13.7) 1,179 (16.8) 3,126 (14.2)
85–89 2,068 (12.9) 1,293 (9.9) 719 (22.5) 2,642 (10.2) 974 (13.9) 2,387 (10.8)
90–94 1,012 (6.3) 665 (5.1) 399 (12.5) 1,278 (4.9) 453 (6.5) 1,224 (5.6)
≥95 288 (1.8) 231 (1.8) 112 (3.5) 407 (1.6) 111 (1.6) 408 (1.9)
Sex Male 8,941 (55.8) 5,263 (40.4) 1,469 (46.0) 12,735 (49.3) 3,440 (49.1) 10,764 (48.8)
Female 7,087 (44.2) 7,752 (59.6) 1,725 (54.0) 13,114 (50.7) 3,568 (50.9) 11,271 (51.2)
BMI* Healthy 4,655 (29.1) 4,548 (34.9) 1,108 (34.7) 8,095 (31.3) 1,953 (27.9) 7,250 (32.9)
Underweight 339 (2.1) 373 (2.9) 98 (3.1) 614 (2.4) 135 (1.9) 577 (2.6)
Overweight 5,995 (37.4) 4,293 (33.0) 1,141 (35.7) 9,147 (35. 4) 2,599 (37.1) 7,689 (34.9)
Obese 4,172 (26.0) 2,442 (18.8) 651 (20.4) 5,963 (23.0) 2,010 (28.7) 4,604 (20.9)
Missing 867 (5.4) 1,359 (10.4) 196 (6.1) 2,030 (7.9) 311 (4.4) 1,915 (8.7)
Smoking status Non-smoker 3,927 (24.5) 2,410 (18.5) 886 (27.7) 5,452 (21.1) 1,626 (23.2) 4,712 (21.4)
Ex-smoker 7,910 (49.0) 7,180 (55.2) 1,865 (58.4) 13,173 (51.0) 3,702 (52.8) 11,336 (51.4)
Current smoker 3,716 (23.3) 2,521 (19.4) 335 (10.5) 5,916 (22.9) 1,487 (21.2) 4,764 (21.6)
Missing 475 (3.2) 904 (6.9) 108 (3.4) 1,308 (5.1) 193 (2.8) 1,223 (5.6)
Rurality Urban 5,997 (37.4) 4,881 (37.5) 1,236 (38.7) 9,642 (37.3) 2,555 (36.5) 8,323 (37.8)
Rural 10,021 (62.5) 8,128 (62.5) 1,957 (61.3) 16,192 (62.6) 4,451 (63.5) 13,698 (62.1)
Missing 10 (0.1) 6 (0.0) 1 (0. 0) 15 (0.1) 2 (0.0) 14 (0.1)
Townsend deprivation quintile 1 (least deprived) 3,709 (23.2) 3,242 (24.9) 815 (25.5) 6,136 (23.7) 1,630 (23.3) 5,321 (24.1)
2 3,497 (21.8) 3,085 (23.7) 763 (23.9) 5,819 (22.5) 1,582 (22.6) 5,000 (22.7)
3 3,210 (20.0) 2,685 (20.6) 670 (21.0) 5,225 (20.2) 1,405 (20.0) 4,490 (20.4)
4 3,047 (19.0) 2,201 (16.9) 528 (16.5) 4,720 (18.3) 1,323 (18.9) 3,925 (17.8)
5 (most deprived) 2,187 (13.6) 1,486 (11.4) 347 (10.9) 3,326 (12.9) 900 (12.8) 2,773 (12.6)
Missing 378 (2.4) 316 (2.5) 71 (2.2) 623 (2.4) 168 (2.4) 526 (2.4)
Comorbidity Atrial fibrillation 2,392 (14.9) 1,152 (8.9) 3,194 (100. 0) 350 (1.4) 923 (13.2) 2,621 (11.9)
Asthma 1,724 (10.8) 1,338 (10.3) 320 (10.0) 2,742 (10.6) 736 (10.5) 2,326 (10.6)
Cancer 1,911 (11.9) 1,328 (10.2) 420 (13.1) 2,819 (10.9) 796 (11.4) 2,443 (11.1)
CHD 5,543 (34.6) 0 (0.0) 1,083 (33.9) 4,460 (17.3) 2,023 (28.9) 3,520 (16.0)
CKD 5,774 (36.0) 0 (0.0) 1,157 (36.2) 4,617 (17.9) 2,343 (33.4) 3,431 (15.6)
COPD 1,470 (9.2) 728 (5.6) 309 (9.7) 1,889 (7.3) 547 (7.8) 1,651 (7.5)
Dementia 737 (4.6) 533 (4.1) 213 (6.7) 1,057 (4.1) 226 (3.2) 1,044 (4.7)
Depression 3,420 (21.3) 2,754 (21.2) 613 (19.2) 5,561 (21.5) 1,413 (20.2) 4,761 (21.6)
Diabetes 4,486 (28.0) 26 (0.2) 658 (20.6) 3,854 (14.9) 1,796 (25.6) 2,716 (12.3)
Epilepsy 287 (1.8) 327 (2.5) 47 (1.5) 567 (2.2) 117 (1.7) 497 (2.3)
Heart failure 1,338 (8.3) 287 (2.2) 651 (20.4) 974 (3.8) 437 (6.2) 1,188 (5.4)
Hypertension 9,666 (60.3) 4,980 (38.3) 2,297 (71.9) 12,349 (47.8) 5,241 (74.8) 9,405 (42.7)
Hypothyroidism 1,724 (10.8) 1,166 (9.0) 440 (13.8) 2,450 (9.5) 755 (10.8) 2,135 (9.7)
Learning disability 54 (0.3) 76 (0.6) 6 (0.2) 124 (0.5) 16 (0.2) 114 (0.5)
Osteoporosis 1,265 (7.9) 1,053 (8.1) 372 (11.6) 1,946 (7.5) 578 (8.2) 1,740 (7.9)
PAD 1,431 (8.9) 0 (0.0) 216 (6.8) 1,215 (4.7) 576 (8.2) 855 (3.9)
Palliative care 223 (1.4) 136 (1.0) 52 (1.6) 307 (1.2) 67 (1.0) 292 (1.3)
Psychosis 262 (1.6) 177 (1.4) 30 (0.9) 409 (1.6) 96 (1.4) 343 (1.6)
Rheumatoid arthritis 394 (2.5) 261 (2.0) 80 (2.5) 575 (2.2) 170 (2.4) 485 (2.2)

Data are given as frequency (percent).

*BMI: healthy (18.5–25.9 kg/m2), underweight (<18.5 kg/m2), overweight (26–30 kg/m2), obese (>30 kg/m2)

BMI, body mass index; CHD, coronary heart disease; CKD, chronic kidney disease; COPD, chronic obstructive pulmonary disease; PAD, peripheral artery disease; TIA, transient ischaemic attack.