Table 2. Significantly (P<0.05) differentially expressed PCOS proteins.
Spot No. | Protein name | Accession No. | MW (kDa) | PI | MOWSE Score | Number of unique peptides | P value | Fold of change (PCOS/Ctrl) |
---|---|---|---|---|---|---|---|---|
2247 | Calmodulin 1 | P62158 | 16.8 | 4.09 | 62 | 3 | 3.4e-005 | 5.09 |
1480 | Protein SET | Q01105 | 33.5 | 4.23 | 54 | 2 | 2.9e-005 | 2.19 |
1713 | 14-3-3 protein epsilon | P62258 | 29.3 | 4.63 | 71 | 2 | 3.9e-005 | 1.94 |
877 | Heat shock protein 90B1 | P14625 | 92.7 | 4.76 | 96 | 3 | 5.2e-005 | 1.84 |
1241 | Calreticulin | P27797 | 48.3 | 4.29 | 83 | 5 | 4.5e-005 | 1.75 |
1248 | Tubulin-β chain | P07437 | 50.1 | 4.78 | 68 | 4 | 3.7e-005 | 1.72 |
1659, 1680 | Polymerase I and transcript release factor | Q6NZI2 | 43.4 | 5.51 | 56 | 2 | 3.0e-005 | 1.56, 1.65 |
1666 | Complement component 1 Q subcomponent-binding protein | Q07021 | 31.7 | 4.74 | 74 | 2 | 4.0e-005 | 1.63 |
2026 | Vimentin | P08670 | 53.7 | 5.06 | 89 | 3 | 4.8e-005 | 1.63 |
833 | Neutral alpha-glucosidase AB | Q14697 | 107 | 5.74 | 72 | 3 | 3.9e-005 | 1.53 |
2280, 2285 | Retinol-binding protein 1 | P09455 | 16.01 | 4.99 | 90, 82 | 3, 2 | 4.8e-005, 4.4e-005 | 1.53, 1.52 |
1931 | Membrane-associated progesterone receptor component 1 | O00264 | 21771.8 | 4.56 | 86 | 5 | 4.9e-005 | 1.51 |
1155 | Antithrombin-III | P01008 | 53.03 | 6.32 | 65 | 3 | 3.5e-005 | 1.5 |
1057 | 78 kDa glucose-regulated protein | P11021 | 72.4 | 5.07 | 81 | 4 | 4.4e-005 | -1.52 |
1265 | Prelamin-A/C | P02545 | 74.4 | 6.57 | 58 | 3 | 3.1e-005 | -1.55 |
1540 | Tropomyosin beta chain | P07951 | 32.9 | 4.66 | 63 | 4 | 3.4e-005 | -1.58 |
998, 1001, 1009, 1026, 1036, 1040, 1043, 1046, 1074, 1075 | Serum albumin | P02768 | 71.3 | 5.92 | 80,72,95,64,71, 54, 59, 48, 75, 82 | 5, 3, 2, 3, 3, 4, 2, 4, 2, 3 | 4.3e-005, 3.9e-005, 5.2e-005, 3.5e-005, 3.9e-005, 2.9e-005, 3.2e-005, 2.6e-005, 4.1e-005, 4.5e-005 | -1.63, -1.58, -1.54, -1.68, -1.72, -1.60, -1.63, -1.71, -1.70, -1.55 |
1030 | Annexin A6 | P08133 | 76.2 | 5.42 | 86 | 3 | 4.7e-005 | -1.77 |