Fig 2. Effect of hJagged-1 and hDll-1 expression in HESS-5 stromal cells on nuclear cell proliferation.

CD133⁺ CB cells (1 × 10⁴) were co-cultured with control (C), hJagged-1 (J1)- or hDll-1 (D1)-expressing HESS-5 stromal cells. (A) Expansion of nuclear cells at 7 days after co-culture. Data are expressed as means ± SD. **P < 0.01, *P < 0.05 between the indicated values. (B) Expanded cell numbers were normalized to cell numbers activated by control HESS-5 stromal cells at day 7. Data are expressed as means ± SD (n = 7 without GSI; n = 4 with GSI). **P < 0.01, *P < 0.05. GSI: γ-secretase inhibitor.