Table 3. Composition of Selected Freeze-dried Lead Formulations for Long-term Stability Study.
Composition | Lead 1 | Lead 2 |
---|---|---|
Sucrose (w/v) | 1% | - |
Trehalose (w/v) | - | 1% |
Glycine (w/v) | 3% | 3% |
Sodium phosphate (mM) | 20 | 20 |
Polysorbate 801 (w/v) | 0.05% | 0.05% |
Hemagglutinin (μg/mL) | 90 | 90 |
pH | 7.2 | 7.2 |
1 Polysorbate 80 was from bulk vaccine and no additional amount was added.