Table 3. Early life food-related symptoms (FRS) or food allergy (FA) severity as a predictor of FRS or FA at 16 years, adjusted analyses*.
A. Risk factors for FRS or FA at 16 years amongst children with early life FRS | B. Risk factors for FA at 16 years amongst children with early life FA | |||||||
---|---|---|---|---|---|---|---|---|
n | N | OR* | 95%CI | n | N | OR* | 95%CI | |
Age at first reaction time | ||||||||
By 2 years | 97 | 246 | 1.00 | 119 | 158 | 1.00 | ||
Between 2 and 4 years | 14 | 63 | 0.42 | 0.22–0.81 | 9 | 14 | 0.56 | 0.17–1.85 |
Symptoms† | ||||||||
Gastrointestinal | 16 | 42 | 1.00 | 13 | 22 | 1.00 | ||
Dermatological‡ | 44 | 109 | 1.22 | 0.57–2.58 | 53 | 65 | 2.94 | 1.00–8.67 |
Respiratory§ | 12 | 16 | 4.65 | 1.26–17.2 | 35 | 41 | 3.50 | 1.00–12.2 |
By specific food† | ||||||||
Milk | 19 | 66 | 1.00 | 21 | 38 | 1.00 | ||
Egg | 9 | 24 | 1.57 | 0.57–4.30 | 11 | 17 | 1.69 | 0.50–5.73 |
Fish | 10 | 32 | 1.15 | 0.45–2.94 | 3 | 5 | 0.84 | 0.12–5.99 |
Peanuts, tree nuts | 18 | 31 | 3.29 | 1.32–8.16 | 24 | 28 | 5.63 | 1.60–19.9 |
Fruit, pips or pits | 11 | 19 | 2.97 | 1.00–8.83 | 16 | 20 | 3.17 | 0.87–11.6 |
Fruit, citrus | 17 | 54 | 1.10 | 0.49–2.47 | 8 | 11 | 2.05 | 0.44–9.45 |
Chocolate | 12 | 28 | 1.17 | 0.67–4.42 | 18 | 24 | 2.27 | 0.72–7.15 |
*Adjusted for sex, parental allergy, socio-economic status and early life allergic multimorbidity
†Categories are not mutually exclusive
‡Urticaria and/or oedema
§Rhinitis and/or wheezing
Bold text denotes statistically significant results