Table 3. KEGG pathway enrichment results for the genes with either up-regulated or down-regulated expression.
| Pathway name | Database | ID | Gene symbols | P-value |
|---|---|---|---|---|
| Lysine degradation | KEGG PATHWAY | rno00310 | Dot1l, Setd2 | 0.0088 |
| Glycosaminoglycan biosynthesis—chondroitin sulfate/dermatan sulfate | KEGG PATHWAY | rno00532 | Dse, Chst13 | 0.0135 |
| Thyroid hormone synthesis | KEGG PATHWAY | rno04918 | Atf6b, Asgr1, Gpx3 | 0.0183 |
| Hematopoietic cell lineage | KEGG PATHWAY | rno04640 | Tfrc, Cd8b | 0.0283 |
| Pyruvate metabolism | KEGG PATHWAY | rno00620 | DLAT, Me3 | 0.0418 |
KEGG, Kyoto Encyclopedia of Genes and Genomes; Dot1l, DOT1-like, histone H3 methyltransferase; Setd2, SET-domain containing 2; Dse, dermatan sulfate epimerase; Chst13, carbohydrate (chondroitin 4) sulfotransferase 13; Atf6b, activating transcription factor 6 beta; Asgr1, asialoglycoprotein receptor 1; Gpx3, glutathione peroxidase 3; Tfrc, transferrin receptor; Cd8b, CD8b molecule; DLAT, dihydrolipoamide S-acetyltransferase; Me3, malic enzyme 3, NADP(+)-dependent, mitochondria.