Table 1. Serum biomarkers in diet groups, excluding animals with liver massesa,b.
HFWD (n = 11)a | HFWD-Ca (n = 10)a | |
---|---|---|
AST (U/L) | 149 ± 115 | 136 ± 45 |
ALT (U/L) | 71 ± 22 | 73 ± 32 |
AlkP (U/L) | 54 ± 23 | 36 ± 16 |
Total bilirubin (mg/dL) | 0.14 ± 0.07 | 0.07 ± 0.05* (p = 0.0189) |
Albumin (g/dL) | 2.94 ± 0.60 | 2.97 ± 0.49 |
Total protein (g/dL) | 5.66 ± 0.97 | 5.93 ± 0.76 |
Creatinine (mg/dL) | 0.18 ±0.04 | 0.17 ± 0.03 |
Glucose (mg/dL) | 252 ± 71 | 243 ± 38 |
Calcium (mg/dL) | 9.30 ± 1.24 | 9.80 ± 0.63 |
a 15 of 20 HFWD and 14 of 20 HFWD-Ca animals had no liver masses. Serum values were not available from 4 non-mass HFWD and 4 non-mass HFWD-Ca animals owing to post-mortem coagulation or insufficient sample.
b Values are mean +/- S.D.
* significantly different by unpaired t tests, two-tailed without multiple comparisons correction
AST Aspartate Aminotransferase, ALT alanine aminotransaminase, ALKP alkaline phosphatase