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. 2016 Nov 16;11(11):e0166178. doi: 10.1371/journal.pone.0166178

Table 1. Serum biomarkers in diet groups, excluding animals with liver massesa,b.

HFWD (n = 11)a HFWD-Ca (n = 10)a
AST (U/L) 149 ± 115 136 ± 45
ALT (U/L) 71 ± 22 73 ± 32
AlkP (U/L) 54 ± 23 36 ± 16
Total bilirubin (mg/dL) 0.14 ± 0.07 0.07 ± 0.05* (p = 0.0189)
Albumin (g/dL) 2.94 ± 0.60 2.97 ± 0.49
Total protein (g/dL) 5.66 ± 0.97 5.93 ± 0.76
Creatinine (mg/dL) 0.18 ±0.04 0.17 ± 0.03
Glucose (mg/dL) 252 ± 71 243 ± 38
Calcium (mg/dL) 9.30 ± 1.24 9.80 ± 0.63

a 15 of 20 HFWD and 14 of 20 HFWD-Ca animals had no liver masses. Serum values were not available from 4 non-mass HFWD and 4 non-mass HFWD-Ca animals owing to post-mortem coagulation or insufficient sample.

b Values are mean +/- S.D.

* significantly different by unpaired t tests, two-tailed without multiple comparisons correction

AST Aspartate Aminotransferase, ALT alanine aminotransaminase, ALKP alkaline phosphatase