Table 5. Transport parameters.

	Value	unit	References
Permeability between normal and blood compartments
VEGF	4.0 × 10−8	cm/s	27
sVEGFR1	1.5 × 10−8	cm/s	30
VEGF:sVEGFR1 complex	1.5 × 10−8	cm/s	30
Permeability between disease and blood compartments
VEGF	4.0 × 10−7	cm/s	Assumed, based on high permeability in PAD
sVEGFR1	3.0 × 10−7	cm/s	Assumed
VEGF:sVEGFR1 complex	1.5 × 10−7	cm/s	Assumed
Clearance
VEGF	1.1 × 10−3	s−1	Calculated, based on half-life
sVEGFR1	5.0 × 10−6	s−1	30
VEGF:sVEGFR1	3.0 × 10−4	s−1	30
α2M	3.9 × 10−5	s−1	31
VEGF:α2M complex	3.9 × 10−5	s−1	Assumed, based on α2M
α2Mfast	3.9 × 10−3	s−1	32
VEGF:α2Mfast complex	3.9 × 10−3	s−1	Assumed, based on α2Mfast
Degradation
sVEGFR1	1.9 × 10−4	s−1	Assumed, based on VEGF
VEGF:sVEGFR1 complex	1.9 × 10−4	s−1	Assumed, based on VEGF
Synthesis
α2M	3.5 × 1010	Molecules/cm3 tissue/s	Calculated
α2Mfast	1.9 × 1010	Molecules/cm3 tissue/s	Calculated