Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2016 Nov 17;6:36736. doi: 10.1038/srep36736

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2016, The Author(s)

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

PMC Copyright notice

(A,B) Immunostaining for Shh and LTL in adjacent P7 control kidneys (A and B, respectively) reveals no obvious Shh expression (A). (C,D) Immunostaining in P7 mutant kidneys shows clusters of ectopic Shh staining in non-dilated tubules (C, arrowhead) that also express LTL in an adjacent section (D, arrowhead), but shows no Shh staining in LTL-positive cyst lining cells (asterisks). (E,F) Higher magnification from regions in panels (C,D) (respectively), confirm that non-dilated Shh-expressing mutant tubules are also LTL-positive (arrowheads), but that LTL-positive cysts do not express Shh (asterisks). (A–D) scale bar = 100 μm.