Table 2.

Univariable and Multivariable Cox Regression for recipient death.

	Univariable			Multivariable
variable	HR	p value	95% CI	HR*	p value	95% CI
Viral Factors
HIV−/HCV−	REF			REF
HCV+	1.75	<0.001	1.66–1.85	1.44	<0.001	1.33–1.56
HIV+	1.22	0.11	0.95–1.55	0.90	0.53	0.66–1.24
HIV+/HCV+	3.38	<0.001	2.53–4.51	2.26	<0.001	1.45–3.52
Recipient Age
Age <40 years	REF			REF
Age 40–60 years	2.25	<0.001	2.14–2.36	1.91	<0.001	1.79–2.03
Age >60 years	4.69	<0.001	4.47–4.92	3.49	<0.001	3.27–3.73
Other recipient factors
Male	0.84	<0.001	0.81–0.86	0.93	0.001	0.90–0.97
African American	1.18	<0.001	1.15–1.22	1.00	0.99	0.96–1.04
Pre-transplant diabetes	2.23	<0.001	2.17–2.30	1.66	<0.001	1.61–1.72
Pre-transplant dialysis	2.21	<0.001	2.10–2.31	1.62	<0.001	1.52–1.73
Years on dialysis	1.05	<0.001	1.05–1.06	1.04	<0.001	1.03–1.04
Transplant Factors
Deceased donor	1.94	<0.001	1.88–2.00	1.33	<0.001	1.27–1.39
Expanded criteria donor	2.26	<0.001	2.18–2.34	-	-	-
CDC high risk donor	0.98	0.64	0.91–1.06	-	-	-
HCV+ donor	2.24	<0.001	2.06–2.43	1.97	<0.001	1.54–2.53
Acute rejection in 1st year	1.22	<0.001	1.17–1.27	-	-	-
HCV donor* HCV recipient	0.59	0.006	0.48–0.74	0.55	<0.001	0.41–0.73
Antibody induction use
Lymphodepleting	REF			REF
Non-lymphodepleting	1.00	0.82	0.96–1.03	1.13	<0.001	1.09–1.17

^*HR is adjusted to reflect tacrolimus based immunosuppression and an interaction term for transplant year and tacrolimus use.