FIG. 10.
Interindividual differences in the thickness of the RNFL in normal eyes. This patient suffered nonarteritic ischemic optic neuropathy in the right eye 4.5 months before these photographs. The RNFL in the right eye is still in the normal range compared to age matched control, but 30 microns thinner than the left eye, which was unaffected. This is because his baseline RNFL is thicker than the average population, which masks the thinning of the RNFL in the right eye when compared to the general population. The left unaffected eye has a RNFL average thickness shown in a white box (black arrow) and has white filled sectors in the RNFL probability thickness plots (lower left panel) indicating a thickness greater than or equal to the top 5 percentile of normal. The RNFL symmetry analysis can help identify patients with unilateral optic neuropathy (red arrow). In addition, the GCL-IPL analysis of the macula demonstrates the severe thinning of the ganglion cell layer in the right eye (lower right image), which correlates with the patient's significant vision loss. GCL-IPL, ganglion cell layer-inner plexiform layer; RNFL, retinal nerve fiber layer.