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. Author manuscript; available in PMC: 2017 Oct 3.
Published in final edited form as: Curr Protoc Neurosci. 2016 Oct 3;77:9.55.1–9.55.17. doi: 10.1002/cpns.15

Figure 3.

Figure 3

Histological (Nissl-stained) examples of NVHL (A-C) and sham (D) brains from adult animals. A, NVHL brain with minimal cell loss and disorganization, indicated by arrows. Anterior-posterior (AP) level is approximately −4.5 mm relative to bregma (Paxinos and Watson, 1988). B, NVHL brain with moderate cell loss and disorganization, indicated by arrows. Approximate AP level, −5.3 mm. C, NVHL brain with extensive cell loss and disorganization, indicated by arrows. Note the enlarged ventricles and slight lateral cortical thinning. Approximate AP level, −5.6 mm. D, Sham-treated brain showing an intact hippocampus. Approximate AP level, −5.6 mm.