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Morphological diversity of pTDP-43 inclusions seeded into HEK cells.A) Diagrammatic illustration of different morphological types of neuronal cytoplasmic inclusions seen in motor neuron cell bodies from patients with ALS. B) Different morphological types of inclusions observed upon seeding of pathological pTDP-43 (green) from ALS patient CNS tissue onto cells expressing FLAG tagged FL WT TDP-43 (red).
