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. Author manuscript; available in PMC: 2016 Nov 17.
Published in final edited form as: J Am Chem Soc. 1992 Apr 1;114(9):3523–3527. doi: 10.1021/ja00035a056

Table I.

The Effects of Varied Loop Size on the Melting Temperature (Tm) of the Complexes of Circular Oligonucleotides with d(A)12 and with a 36mer Containing the d(A)12 Sequencea

circle loop size (nt) Tm of complex (°C)
12mer substrate 36mer substrate
graphic file with name nihms828028t1.jpg 3 49.2
graphic file with name nihms828028t2.jpg 4 54.9 49.7
graphic file with name nihms828028t3.jpg 5 58.6 56.2
graphic file with name nihms828028t4.jpg 6 55.8 52.3
graphic file with name nihms828028t5.jpg 10 54.1
a

See text for 36mer sequence and for experimental conditions.