Fig. 2. Examples of the effect of lateral PB block on noxious stimulus-evoked, reflex-related activity of ON- and OFF-cells.
Representative examples show OFF- and ON-cell activity during withdrawal from noxious heat stimulus at baseline compared to during lidocaine block of lateral PB contralateral to the stimulus, as well as subsequent recovery. In both cases, reflex-related changes in firing were substantially reduced, although not entirely eliminated. Increased spontaneous firing of the OFF-cell is also evident.