TABLE 2.

Clinical and laboratory features in infant with and without genetically proven mitochondrial liver disease as a cause of liver failure

	Genetically proven MLD (n = 5)	Other causes of ALF (n = 34)	P
Birth weight, kg	2.6 (2.3–2.9)	2.8 (1.8–4.1)	0.76
Age at presentation, days	110 (9–503)	16 (1–689)	0.33
Prothrombin time, s	26 (23–41)	34 (18–120)	0.5
Serum bilirubin, μmol/L	113 (34–335)	146 (5–492)	0.79
ALT, IU/L	113 (42–1875)	940 (19–6000)	0.11
Lactate, mmol/L	7.2 (3.7–25)	4.3 (0.7–22.4)	0.11

ALF = acute liver failure; ALT = alanine aminotransferase; MLD = mitochondrial liver disease.